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What causes thrombophlebitis after hysterectomy?

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Final answer:

Thrombophlebitis after a hysterectomy is primarily caused by reduced mobility leading to venous stasis and hypercoagulation due to the body’s natural response to surgery. Underlying conditions like thrombophilia can further increase the risk of thrombus formation that can obstruct blood vessels.

Step-by-step explanation:

The cause of thrombophlebitis after a hysterectomy involves factors such as vessel damage to the endothelial lining that activates the clotting mechanism. This may lead to venous stasis, a condition where blood remains stationary for long periods typically in the legs, increasing the risk of thrombus formation. Additionally, thrombophilia (hypercoagulation) which is a tendency to form thrombosis, whether familial or acquired, can lead to thrombosis. Acquired factors that might contribute include autoimmune diseases, immune reactions to medication, and conditions such as obesity or pregnancy.

After surgery like a hysterectomy, the body experiences an increased risk of blood clots (thrombosis) due to factors such as reduced mobility (leading to venous stasis) and the body's natural response to surgery, which includes activation of the clotting cascade to heal surgical wounds. This heightened state of coagulation can result in the formation of a thrombi that can block vessels (occlusive thrombus) or adhere to vessel walls (mural thrombus), particularly if the patient has an underlying hypercoagulable state.

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