Question

Why is penicillin administered with Procaine? With Probenecid?

a) To enhance its antimicrobial effect
b) To reduce allergic reactions
c) To prolong its action in the body
d) To mitigate gastrointestinal side effects

Answer 1

c) To prolong its action in the body

Penicillin is combined with Procaine and Probenecid to prolong its action in the body, allowing for sustained therapeutic levels of the antibiotic.

Step-by-step explanation:

Penicillin is often administered with Procaine to prolong its action in the body. This combination allows for a slower release and a longer duration of the antibiotic's presence in the bloodstream. On the other hand, Penicillin is paired with Probenecid to achieve the same goal of prolonging its effect. Probenecid inhibits the renal excretion of penicillin, thereby increasing its concentration in the blood. Therefore, the correct answer for why penicillin is administered with Procaine and Probenecid is c) To prolong its action in the body.