Final answer:
The statement that oil-based rectal suppositories should be kept refrigerated is true because they are designed to melt at body temperature and therefore could melt at room temperature, affecting their shape and effectiveness.
Step-by-step explanation:
The statement 'Rectal suppositories with an oil base should be kept refrigerated' is generally true. The oil base in rectal suppositories is designed to melt at body temperature, providing the mechanism for the medication to be released. However, if these suppositories were kept at room temperature, especially in warmer environments, they could melt and become deformed, which can lead to difficulties in administration and potentially reduce the effectiveness of the medication.
To maintain their shape and efficacy, it is advised that rectal suppositories with an oil base are stored in a refrigerator. It is also important to follow the specific storage instructions provided by the manufacturer or pharmacist, as some formulations may have different requirements.