Final answer:
Death from sickle cell anemia is most likely to occur in young adulthood due to reduced oxygen perfusion caused by the disease's characteristic sickle-shaped red blood cells. Life expectancy can vary, and with modern treatments, some individuals live into middle adulthood. The persistence of the sickle-cell gene is partly due to the protection it provides against malaria.
Step-by-step explanation:
Sickle cell anemia is a genetic disease in which red blood cells take on a sickle shape. Death from sickle cell anemia is most likely in young adulthood. The sickle shape of the cells reduces oxygen perfusion into the blood, leading to various complications that can affect life expectancy. However, with modern medical care, some individuals with sickle cell anemia may live into their 40s or beyond. It's important to note that life expectancy for those with sickle cell anemia can vary based on the quality of healthcare and access to treatment.
Many people with the sickle-cell genetic mutation die at an earlier age compared to those without the mutation. One reason why the sickle-cell gene remains relatively common, especially among people of African descent, is its association with some degree of protection against malaria, which is prevalent in parts of Africa. This genetic advantage in malaria-prone regions contributes to its persistence despite its negative impact on overall health.