Final answer:
Pre-eclampsia is associated with increased blood pressure and can cause the neuromuscular system to become more irritable. The correct answer to whether pre-eclampsia makes the neuromuscular system more or less irritable is 'a) more'.
Step-by-step explanation:
Pre-eclampsia is a condition related to pregnancy that typically occurs after 20 weeks of gestation and is characterized by increased blood pressure and often proteinuria. It makes the neuromuscular system more irritable. This is due to an increase in reflex irritability, which can sometimes lead to convulsions, a condition known as eclampsia. Although Pre-eclampsia does not directly involve sodium (Na+) levels, imbalances such as decreased Na+ levels can contribute to its complexity.
Considering the given options, the most direct answer to the question 'Pre-eclampsia makes the neuromuscular system more or less irritable?' would be 'a) more'. Increased blood pressure a keynote feature of pre-eclampsia, can cause various complications throughout the body, including increased neuromuscular excitability.