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The BRCA1 and BRCA2 genes are master genes that regulate other genes in the cell-such as the genes responsible for cell growth and replication and DNA repair. If these
genes are damaged or altered through mutation, then it might affect the cell's control over the processes of cell growth and replication or the ability to repair DNA.
Imagine a study looking at the effect of BRCA1 and BRCA2 on breast cancer in women. The researchers found subjects who did not have breast cancer and identified whether
they had a mutation in BRCA1, a mutation in BRCA2, or no mutation in either of the BRCA genes. (This study did not-include people who had mutations in both BRCA1 and
BRCA2.) The researchers identified the genes of each subject and then collected data from all the subjects during a 30-year period to determine how many eventually
developed breast cancer. The following table presents the results of this hypothetical study. Use the data to determine the percentage of subjects in each group who
developed breast cancer. Type that percentage number into the table where indicated.

Total points: 3/5 Attempts The BRCA1 and BRCA2 genes are master genes that regulate-example-1
User Wolfcall
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Answer:

BRCA1 Mutation: 60%

BRCA2 Mutation: 60%

No BRCA Mutation: 12%

Step-by-step explanation:

For the BRCA1 Mutation group, the percentage of subjects who developed breast cancer is calculated as (588 / 980) * 100, which equals 60%.

Similarly, for the BRCA2 Mutation group, the percentage is (612 / 1020) * 100, also equating to 60%.

In the No BRCA Mutation group, the percentage is (125 / 1040) * 100, resulting in 12%.

User Adriano Almeida
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