Final answer:
Nerve cells are the ones that cannot divide or be replaced when damaged by disease, in contrast to stem cells and skin cells which can regenerate.
Step-by-step explanation:
The cells that are not capable of cell division and cannot be replaced when they are destroyed by disease are nerve cells. Unlike stem cells, which have the ability to continuously divide and differentiate into various cell types, and skin cells, which routinely regenerate to repair wounds, most nerve cells do not have the capacity for regeneration. This lack of regenerative ability means that damaged nerve tissues often lead to permanent consequences such as paralysis. Similarly, certain types of muscle cells, specifically skeletal muscle fibers and cardiac muscle cells, also do not typically divide, but they are not mentioned as an option in the provided question.