Final answer:
The combination of hydralazine and isosorbide dinitrate is an effective adjunct therapy for CHF in African Americans. It is used to improve symptoms of heart failure and hypertension, and to slow irregular heartbeats such as atrial fibrillation.
Step-by-step explanation:
An adjunct therapy for CHF (congestive heart failure) that can be used specifically in African Americans is a combination of hydralazine and isosorbide dinitrate. This combination is used to treat or improve symptoms of cardiovascular conditions, including high blood pressure and heart failure.
It is particularly noted for being effective in African American patients, especially when patients are not responding well to ACE inhibitors and diuretics. Additionally, this therapy has a beneficial effect in slowing certain types of irregular heartbeat (arrhythmias), such as atrial fibrillation.
The importance of culturally tailored treatment approaches, like the use of this combination therapy in African Americans, highlights the need for personalized medicine and can be seen in the context of promoting health equities through community-based participatory research methods.