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How does randomization in a clinical trial controls confounding variables such as age of the participants or pre-existing conditions?

User Chantell
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Final answer:

Randomization in a clinical trial controls confounding variables by ensuring that participants are randomly assigned to treatment groups, which helps distribute the variables evenly across the groups. This allows researchers to isolate the effects of the treatments being studied.

Step-by-step explanation:

In a randomized clinical trial, randomization is used to control confounding variables such as age of participants or pre-existing conditions. By randomly assigning participants to different treatment groups, researchers ensure that the groups are similar in terms of these variables. Randomization helps to distribute confounding variables evenly across the groups, making it easier to isolate the effects of the treatments being studied.

For example, let's say a clinical trial is testing the effectiveness of a new drug for treating a certain condition. If age is a potential confounding variable that could influence the response to the drug, random assignment of participants to treatment groups ensures that both younger and older participants are evenly distributed across the groups. This allows researchers to compare the outcomes of the two groups and determine if the drug has a specific effect on the condition, independent of age.

By controlling for confounding variables through randomization, researchers can make more accurate conclusions about the effects of the treatments being studied.

User Tomasz Dziurko
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