Final Answer:
The correct answer is
3) Absence of lipids.
Step-by-step explanation:
Lipids, also known as fats, are an essential component of Total Parenteral Nutrition (T.P.N.). T.P.N. is a method of providing nutrition intravenously to individuals who cannot obtain adequate nutrition through oral or enteral routes. It typically consists of macronutrients, including carbohydrates, proteins, and lipids. The absence of lipids in T.P.N. would be an atypical and non-defining characteristic, as lipids play a crucial role in providing a concentrated source of energy.
Firstly, lipids are highly calorie-dense, providing approximately 9 calories per gram, compared to 4 calories per gram for both carbohydrates and proteins. This high calorie content is important for patients who require T.P.N. to meet their energy needs. Therefore, the presence of lipids is essential for achieving the high calorie content associated with T.P.N. formulations.
Secondly lipids contribute to the formulation's osmolarity. The absence of lipids may result in an inadequate osmolarity level, impacting the stability of the T.P.N. solution. Adequate osmolarity is crucial to prevent complications such as phlebitis and thrombophlebitis at the infusion site.
In conclusion the absence of lipids in T.P.N. contradicts the typical composition of this nutritional intervention affecting both the calorie content and osmolarity. Thus, option 3) "Absence of lipids" is not a defining characteristic of T.P.N. formulations.