Final answer:
High Fe, low ferritin, and low Fe binding capacity can have multiple causes, including iron overload, decreased hemoglobin formation, abnormalities in serum iron concentration, or abnormal pigment deposition in tissues.
Step-by-step explanation:
The cause of high Fe (iron), low ferritin, and low Fe binding capacity can be due to iron overload, decreased formation of hemoglobin, abnormalities in the serum iron concentration, or abnormal deposition of iron-combining pigments in the tissues. Excessive iron administration or hereditary diseases like haemochromatosis can lead to iron overload, resulting in high levels of iron and low ferritin. Decreased formation of hemoglobin or abnormalities in the serum iron concentration can also cause imbalances in iron levels. Additionally, abnormal deposition of iron-combining pigments in the tissues can affect iron binding capacity.