Final answer:
The peptide bond is indeed an amide linkage formed by the reaction between the carboxyl group of one amino acid and the amino group of another, which is true. The peptide bond links these two amino acids, forming a dipeptide without involving their side chains.
Step-by-step explanation:
The statement that the peptide bond is an amide linkage generated by the reaction between the carboxyl group of one amino acid and the amino group of another amino acid is true. When two amino acids form this bond, the carboxyl group of the first amino acid (C-terminus) reacts with the amino group (N-terminus) of the second amino acid. This reaction results in the elimination of a water molecule, yielding a covalent bond known as the peptide bond, which links the two amino acids together.
For example, if the amino acid alanine reacts with glycine, their respective amino and carboxyl groups will form a peptide bond through a dehydration reaction. The R groups (side chains) do not participate in the formation of a peptide bond; they simply remain attached to the alpha carbons of the amino acids. Peptide bonds are fundamental to the structure of proteins, and through successive reactions, they can create long chains called polypeptides which eventually fold into functional proteins.