Question

Draw the most stable chair conformation of compounds.

Answer 1

To draw the most stable chair conformation of compounds, start by drawing a hexagon shape to represent the cyclohexane ring. Add bond lines to create the chair skeleton, and then draw axial and equatorial bonds. Finally, place substituents in the equatorial positions to increase stability.

Step-by-step explanation:

To draw the most stable chair conformation of compounds, follow these steps:

1. Start by drawing a hexagon shape to represent the cyclohexane ring.
2. Add bond lines connecting the corners of the hexagon to create the chair skeleton.
3. Draw upward and downward lines from each corner of the chair skeleton to represent the axial bonds.
4. Draw lines parallel to the axial bonds, but one bond away, to represent the equatorial bonds.
5. Place substituents on the axial or equatorial positions based on their size and steric interactions.

The most stable conformation is the one that minimizes steric interactions between bulky substituents, typically by placing them in the equatorial positions. This reduces 1,3-diaxial interactions and increases stability.