Final answer:
In microbiology, a substance is considered mutagenic if the number of bacterial colonies on its plate is greater than 30-300 colonies. This range allows for statistically reliable numbers and accurate counting of individual colonies.
Step-by-step explanation:
In microbiology, a substance is considered mutagenic if the number of bacterial colonies on its plate is greater than the range of 30-300 colonies. This is because plates with too few colonies are not statistically reliable, while overcrowded plates make it difficult to count individual colonies accurately.
The range of 30-300 colonies also reduces the occurrence of multiple bacterial cells forming a single colony, allowing for a more accurate calculation of the colony-forming units (CFU) and the true number of live bacteria in the population.