Final answer:
Facilitated diffusion and active transport both involve the movement of substances across a membrane, but they differ in terms of their use of energy and the direction of movement.
Step-by-step explanation:
Facilitated diffusion and active transport both involve the movement of substances across a membrane. They both require the use of specific membrane proteins for transportation. However, facilitated diffusion moves substances down their concentration gradient without the use of energy, while active transport moves substances against their concentration gradient using energy in the form of ATP.