Final answer:
The increased work of breathing associated with auto-PEEP during mechanical ventilation is due to hyperinflation or impaired contractility of the diaphragm, large alveolar pressure drops required to trigger breaths, and increased volume of the intrathoracic airways.
Step-by-step explanation:
The increased work of breathing associated with auto-positive end-expiratory pressure (PEEP) during mechanical ventilation is due to:
- I. Hyperinflation or impaired contractility of the diaphragm
- II. Large alveolar pressure drops required to trigger breaths
- III. Increased volume of the intrathoracic airways
The correct answer is D) I, II, and III. This means that all three factors are involved in the increased work of breathing associated with auto-PEEP during mechanical ventilation. Hyperinflation or impaired contractility of the diaphragm, large alveolar pressure drops required to trigger breaths, and increased volume of the intrathoracic airways all contribute to the increased effort required to breathe.