Question

Can aminoglycosides be administered orally (PO)?

A) Yes, aminoglycosides are commonly given orally for optimal absorption.
B) No, aminoglycosides are not effective when administered orally due to poor absorption.
C) Yes, but only specific aminoglycosides are suitable for oral administration.
D) Yes, but oral administration is reserved for specific medical conditions.

Answer 1

No, aminoglycosides are not effective when administered orally due to poor absorption.

Step-by-step explanation:

Aminoglycosides are not commonly administered orally (PO) because they have poor absorption in the gastrointestinal (GI) tract. These drugs are usually given through intravenous or intramuscular injection to ensure optimal therapeutic drug levels are achieved. Some aminoglycosides, such as neomycin, have been formulated as topical preparations for the treatment of superficial skin infections. Therefore, option B) No, aminoglycosides are not effective when administered orally due to poor absorption is the correct answer.