Final answer:
Cushing's syndrome is the adrenal cortex disease characterized by excess production of cortisol, typically caused by a pituitary tumor.
Step-by-step explanation:
The adrenal cortex disease associated with an excess production of cortisol is Cushing's syndrome. This condition is most commonly caused by a pituitary tumor that leads to an overproduction of the hormone ACTH, subsequently causing the adrenal cortex to secrete excessive amounts of cortisol. Some manifestations of Cushing's syndrome include obesity, diabetes, high blood pressure, osteoporosis, and psychological changes such as depression. Treatment for Cushing's syndrome will differ based on its cause and may involve surgery, medication, or other therapies to reduce cortisol levels.