Final Answer:
When initiating a new prescription for clozapine in a schizophrenic client due to several critical reasons. Therefore, the correct answer is option D. Renal function tests, coagulation profile
Step-by-step explanation:
The prescription of clozapine for a schizophrenic client necessitates monitoring specific laboratory parameters to ensure the patient's safety and manage potential side effects. Option D, which includes renal function tests and a coagulation profile, is the most pertinent choice. Clozapine can impact the kidneys, so assessing renal function is crucial to detect any potential impairment. Additionally, monitoring the coagulation profile is essential as clozapine may influence blood clotting factors, warranting close observation to prevent adverse events.
Renal function tests typically include assessments such as serum creatinine and blood urea nitrogen (BUN), providing insights into the kidney's filtration capability. Coagulation profiles encompass tests like prothrombin time (PT) and activated partial thromboplastin time (aPTT), evaluating the blood's clotting mechanism.
Regular monitoring of these parameters helps in early detection of any abnormalities, allowing for timely intervention and adjustment of the treatment plan if necessary. This comprehensive approach aligns with the best practices in psychiatric care, ensuring the well-being of the patient while on clozapine therapy.