Question

While taking fluoxetine, why should a client avoid ibuprofen?

A. Increased risk of gastrointestinal bleeding
B. Potential allergic reactions
C. Reduced effectiveness of fluoxetine
D. Elevated risk of serotonin syndrome

Answer 1

Taking fluoxetine and ibuprofen together can increase the risk of gastrointestinal bleeding.

Step-by-step explanation:

When taking fluoxetine, a client should avoid ibuprofen because it can increase the risk of gastrointestinal bleeding.

Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases the levels of serotonin in the brain. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, decreases fever, and decreases inflammation. NSAIDs, including ibuprofen, can interfere with the function of platelets, which are responsible for blood clotting. This interference can lead to an increased risk of gastrointestinal bleeding when combined with fluoxetine.