Final answer:
The best nursing intervention would be to remove the anti-embolism stockings to alleviate symptoms and promote proper circulation.
Step-by-step explanation:
The best nursing intervention in this case would be to remove the anti-embolism stockings. The presence of edema and deep creases from the stockings indicates that they are causing a restriction of blood flow and contributing to the coldness of the patient's toes. By removing the stockings, the nurse can promote proper circulation and alleviate the symptoms. Additionally, the nurse should assess the patient's condition further to determine if any additional interventions are necessary.