Question

A nurse is evaluating a client who is receiving amphotericin B via intermittent IV bolus. Which of the following findings indicates an adverse reaction to this medication?

A. O_2 saturation 94%
B. Insertion site pain level of 6 on a scale of 0 to 10
C. Urinary output 70 mL/2 hr
D. Speech slurred

Answer 1

Among the effects listed, a urinary output of 70 mL/2 hr after administration of amphotericin B indicates a possible adverse reaction linked to nephrotoxicity and decreased renal function.

Step-by-step explanation:

A student is questioning which finding might indicate an adverse reaction to the medication amphotericin B when given via intermittent IV bolus. Among the listed possible outcomes, urinary output 70 mL/2 hr is notably concerning and can be indicative of an adverse effect. Amphotericin B is known to cause nephrotoxicity, which can lead to renal damage and reduced urinary output. Therefore, a urinary output of 70 mL over 2 hours could suggest that renal function might be compromised. Regular monitoring of renal function, including urinary output, is crucial when administering amphotericin B.