Final answer:
A client with Cushing's disease is at risk for metabolic alkalosis due to the chronic hypersecretion of adrenocorticotrophic hormone (ACTH). Other causes of metabolic alkalosis include vomiting, diuretic use, and laxative abuse.
Step-by-step explanation:
A client with Cushing's disease is at risk for metabolic alkalosis.
Cushing's disease is characterized by chronic hypersecretion of adrenocorticotrophic hormone (ACTH) by the anterior pituitary gland. This results in elevated aldosterone levels and an increased loss of potassium through urinary excretion. As a consequence, the client can experience a chronic excess of bicarbonate in the blood, leading to metabolic alkalosis.
Other causes of metabolic alkalosis include the loss of hydrochloric acid from the stomach through vomiting, potassium depletion due to diuretic use for hypertension, and excessive use of laxatives.