Final answer:
The correct client response that indicates an understanding of taking alendronate medication is to take it with 8 ounces of water.
Step-by-step explanation:
The correct client response that indicates an understanding of the teaching for alendronate medication is option D: "I will take the medication with 8 ounces of water."
Alendronate is a medication used to treat and prevent osteoporosis. It is important to take it with a full glass of water and while in an upright position to avoid irritation of the esophagus. Taking it with food, antacids, or lying down can interfere with its absorption or cause side effects.