Final answer:
Third-degree burns fully extend into both the epidermis and dermis, resulting in destruction of tissue and affected nerve endings, requiring medical attention and possibly grafting for healing.
Step-by-step explanation:
The major distinction between partial-thickness and full-thickness burns is that third-degree burns involve damage that fully extends into both the epidermis and dermis, destroying the tissue and affecting the nerve endings and sensory functions. These serious burns may appear white, red, or black and require immediate medical attention; they cannot heal on their own and will worsen without proper care. In contrast, partial-thickness burns, such as first-degree and second-degree burns, involve less severe damage and typically heal by themselves or with minimal care. Third-degree burns, being full-thickness burns, often require excision or debridement, and possibly even grafting with skin from an unaffected body part or from skin grown in tissue culture.