Question

Which statements below CORRECTLY describe how ACE Inhibitors work? Select all that apply:

A. This group of medications inhibits the renin-angiotensin-aldosterone system (RAAS).
B. ACE Inhibitors prevent the conversion of Angiotensin I to Angiotensin II.
C. ACE Inhibitors prevent Angiotensinogen from converting to Angiotensin I.
D. ACE Inhibitors have a positive chronotropic and negative inotropic effect on the heart.

Answer 1

ACE Inhibitors block the ACE enzyme to prevent Angiotensin I from being converted to Angiotensin II, leading to vasodilation and reduced blood pressure, without affecting the conversion of Angiotensinogen to Angiotensin I.

Step-by-step explanation:

ACE Inhibitors, or Angiotensin-Converting Enzyme Inhibitors, are a group of medications that significantly influence the renin-angiotensin-aldosterone system (RAAS) and cardiovascular health. They function by blocking the ACE enzyme, which prevents the conversion of Angiotensin I to Angiotensin II, a potent vasoconstrictor that raises blood pressure. This suppression results in vasodilation, lowering blood pressure, and decreasing the workload on the heart. ACE Inhibitors do not inhibit the conversion of Angiotensinogen to Angiotensin I, nor do they generally have a positive chronotropic effect. Instead, they have a negative chronotropic and inotropic effect on the heart, which means they decrease both the heart rate and the force of its contraction.