Final answer:
A patient with heart failure would most benefit from an ACE Inhibitor because it helps in reducing blood pressure and the heart's workload, which is crucial for managing heart failure.
Step-by-step explanation:
The patient who would most benefit from an ACE Inhibitor is Option 3: A patient with heart failure. Angiotensin-converting enzyme (ACE) inhibitors are used to treat or improve symptoms of cardiovascular conditions including high blood pressure and heart failure. These medications block the conversion of angiotensin I to angiotensin II, leading to a decrease in blood pressure and a reduction in the workload on the heart, which is particularly beneficial for patients with heart failure.