Question

HCTZ is a thiazide diuretic administered to promote?

Option 1: Sodium retention
Option 2: Potassium excretion
Option 3: Water reabsorption
Option 4: Calcium absorption

Answer 1

HCTZ, a thiazide diuretic, promotes sodium retention and reduces potassium excretion. It works by inhibiting the Nat/Cl-symporter in the DCT and collecting duct, leading to increased sodium reabsorption and water reabsorption.

Step-by-step explanation:

HCTZ, a thiazide diuretic, is administered to promote sodium retention and decrease potassium excretion. It works by inhibiting the Nat/Cl-symporter in the distal convoluted tubule (DCT) and collecting duct, resulting in increased sodium reabsorption. This increases water reabsorption and reduces urine volume.