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Decreased K+ Output

-- Acute or chronic oliguria (eg, severe ECV deficit, end-stage renal disease).
-- Adrenal insufficiency.
-- Use of potassium-sparing diuretics a. Hypokalemia
b. HYPERnatremia c. Hyponatremia
d. Hyperkalemia

User Tkiethanom
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Final answer:

Decreased potassium output due to various conditions such as oliguria, adrenal insufficiency, or use of potassium-sparing diuretics can lead to hyperkalemia, an elevated potassium level in the blood, with serious implications for heart function and overall health.

Step-by-step explanation:

The conditions described such as acute or chronic oliguria, adrenal insufficiency, and the use of potassium-sparing diuretics all can lead to a decreased excretion of potassium (K+) from the body, resulting in the accumulation of potassium in the bloodstream. This condition is known as hyperkalemia, which is a state of elevated potassium blood levels with a range of symptoms including malaise and potentially fatal cardiac arrhythmias. In contrast, hypokalemia refers to abnormally low potassium blood levels, which can occur due to decreased intake or excessive loss of potassium through vomiting, diarrhea, or alkalosis. Hyperkalemia can impair the function of skeletal muscles, the nervous system, and the heart due to the partial depolarization of cell membranes. It can lead to potentially fatal complications if the heart cannot relax after a contraction and ceases to pump blood effectively. Moreover, in disease states, particularly those affecting kidney function and adrenal cortex activity, potassium regulation is significantly impacted resulting in various electrolyte imbalances.

User Aalexander
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