Final answer:
Corticosteroids are the adjuvant drugs that effectively relieve pain caused by inflammation and bone metastasis, although NSAIDs and opioid analgesics can also play a role in pain management.
Step-by-step explanation:
The adjuvant drug that relieves pain caused by inflammation and bone metastasis is corticosteroids. Corticosteroids are effective in reducing inflammation and can be helpful in managing the pain associated with conditions such as arthritis and bone metastasis, where the cancer has spread to the bones, causing significant pain and inflammation. Nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin and ibuprofen can also manage pain and inflammation, but they may not be as effective as corticosteroids in cases of bone metastasis. Opioid analgesics are very effective pain relievers that may be used when other medications are insufficient, but due to their risk of addiction, their use is generally recommended for the short term and under a doctor's supervision. Lastly, antidepressants are less commonly used for pain relief and are unlikely to be the primary treatment for pain associated with bone metastasis unless the patient is also experiencing depression.