Question

Which drugs may provide relief from bone pain? Select all that apply.

Option 1: Calcitonin
Option 2: Gabapentin
Option 3: Nortriptyline
Option 4: Bisphosphonates
Option 5: Infusional lidocaine

Answer 1

Calcitonin and bisphosphonates directly aid in bone pain relief by targeting bone tissue, while gabapentin, nortriptyline, and infusional lidocaine may also provide relief.

Step-by-step explanation:

Drugs that may provide relief from bone pain include calcitonin, which is used in the treatment of conditions like osteoporosis and Paget's disease, and works by slowing the rate of bone loss. Another class of drugs known as bisphosphonates also helps maintain bone density by decreasing the activity of osteoclasts, which break down bone tissue, thereby reducing the risk of fractures and providing pain relief. Gabapentin and nortriptyline, while not directly targeting bone tissue, are used to treat neuropathic pain and may aid in alleviating bone pain as well. Finally, infusional lidocaine, an anesthetic, can be used to manage severe and refractory pain, though typically in a clinical setting.