Final answer:
Raloxifene, used to treat osteoporosis, is administered orally in tablet form, which is suitable for home use by the patient.
Step-by-step explanation:
The appropriate route of administration for raloxifene, which is prescribed as part of a treatment plan for osteoporosis in a postmenopausal woman, is oral. Therefore, the nurse would instruct the patient to take raloxifene by mouth. Raloxifene is provided in tablet form and is designed for easy home administration without the need for medical assistance such as with injections or specialized applications.