Question

What is the critical Rh antibody titer associated with hydrops/demise?

a) 1:2
b) 1:4
c) 1:8
d) 1:16

Answer 1

The critical Rh antibody titer associated with hydrops or fetal demise is 1:16, and it's an important factor in the prevention of hemolytic disease of the newborn (HDN) or erythroblastosis fetalis in sensitized Rh-negative mothers.

Step-by-step explanation:

The critical Rh antibody titer associated with hydrops or fetal demise is 1:16. A critical titer is considered the level at which the mother's antibodies are sufficient to cause hemolysis of the fetal red blood cells, potentially resulting in hemolytic disease of the newborn (HDN) or erythroblastosis fetalis. This is a significant concern for Rh-negative mothers who have previously been sensitized to Rh-positive blood, either through transfusion or a prior pregnancy with an Rh-positive baby. To prevent HDN, interventions such as the administration of Rho(D) immune globulin are undertaken.