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Bethesda staging of cervical dysplasia:**

**Question:**
What is the Bethesda staging category for cervical dysplasia characterized by atypical squamous cells of undetermined significance (ASC-US)
a. Low-grade squamous intraepithelial lesion (LSIL)
b. High-grade squamous intraepithelial lesion (HSIL)
c. Carcinoma in situ (CIS)
d. Normal cervical cytology

1 Answer

6 votes

Final answer:

The Bethesda staging category for cervical dysplasia characterized by ASC-US is most closely related to LSIL, which indicates mild abnormalities with low potential for progression to cervical cancer.

Step-by-step explanation:

The Bethesda staging category for cervical dysplasia characterized by atypical squamous cells of undetermined significance (ASC-US) is not technically a staging category but a classification used in cytology reports. However, to answer the student's question, the correct category from the provided options that ASC-US might most closely relate to is a. Low-grade squamous intraepithelial lesion (LSIL). LSIL signifies changes in the size, shape, and other characteristics of cervical cells that may be caused by human papillomavirus (HPV) infection and are considered to have low potential for progression to cervical cancer. It's important to note that ASC-US is not an immediate indication of high-grade lesions or cancer, and further testing is often recommended, such as HPV testing, to guide potential further action.

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