Final answer:
Complete moles and increased maternal age are factors associated with a higher risk of subsequent malignant neoplasia in GTD, as complete moles have a greater potential to become malignant, and age-related mutations can increase risks.
Step-by-step explanation:
The factors of Gestational Trophoblastic Disease (GTD) that are associated with a higher risk of subsequent malignant neoplasia include b. complete mole, and the risks associated with maternal factors, such as increased maternal age. A complete mole has a higher potential to develop into Gestational Trophoblastic Neoplasia (GTN), which can include malignant diseases like choriocarcinoma. Moreover, maternal age is a significant factor, as increased risks of translocation mutations and other genetic abnormalities can raise the likelihood of GTD progressing to GTN. Term pregnancies, previous live births, and maternal lifestyle do not specifically increase the risk of GTD progressing to malignancy.