Final answer:
Ovarian cancer must be ruled out in a premenarchal or postmenopausal female with a palpable ovary or adnexal mass. Other conditions such as endometriosis, leiomyoma, and PCOS may also cause palpable masses but are less likely to be associated with cancer.
Step-by-step explanation:
In a premenarchal or postmenopausal female with a palpable ovary or adnexal mass, ovarian cancer must be ruled out. This is because ovarian cancer can present as an ovarian or adnexal mass, and it is more common in postmenopausal women. Other conditions such as endometriosis, leiomyoma, and polycystic ovary syndrome (PCOS) may also cause palpable masses, but they are less likely to be associated with cancer.