Question

What is required for diagnosis of ACIS of the cervix?

a) Positive HPV test
b) Endocervical curettage (ECC)
c) Cone biopsy
d) Colposcopy with biopsy

Answer 1

Colposcopy with biopsy is required to diagnose adenocarcinoma in situ (AIS) of the cervix, although additional diagnostic measures like a Pap smear and HPV test are commonly used to detect abnormal cells.

Step-by-step explanation:

To diagnose Adenocarcinoma in situ (AIS) of the cervix, a colposcopy with biopsy is required. During this procedure, the physician uses a colposcope to closely examine the cervix and then takes a biopsy of any areas that appear abnormal. The biopsy sample is then microscopically examined for pre-cancerous cells. Other diagnostic tools, such as a Pap smear, can detect abnormal cells, but a biopsy is needed to confirm the diagnosis of AIS. A positive HPV test is also indicative of a potential issue, as HPV is closely associated with cervical cancer, but this alone cannot diagnose AIS. Endocervical curettage (ECC) and a cone biopsy might also be performed to obtain diagnostic tissue from higher up in the cervical canal.