Final answer:
Late-onset Alzheimer's disease is the most common form of the disease that occurs after the age of 65. Two examples of SNPs playing a role in susceptibility to this disease are the APOE gene variant E4 and the CLU gene variant. Scientists analyze the role of SNPs using genome-wide association studies (GWAS) and functional studies.
Step-by-step explanation:
Late-onset Alzheimer's disease is a form of the disease that typically occurs after the age of 65. It is the most common form of Alzheimer's and is thought to have a genetic component. One example of a single nucleotide polymorphism (SNP) playing a role in susceptibility to late-onset Alzheimer's is the APOE gene variant E4. Another example is the CLU gene variant.
To analyze the role of SNPs in late-onset Alzheimer's disease, scientists use techniques such as genome-wide association studies (GWAS). GWAS compares the genomes of individuals with and without the disease to identify SNPs associated with increased risk. Additionally, functional studies are conducted to understand how these SNPs affect the expression or function of genes involved in the disease.