Question

Cytoplasmic sensors for viral RNAs, the activation of which leads to type I interferon activation-

a) Toll-like receptors
b) NOD-like receptors
c) RIG-I-like receptors
d) C-type lectin receptors

Answer 1

The cytoplasmic sensors for viral RNAs that activate type I interferon are the RIG-I-like receptors (RLRs)

Step-by-step explanation:

The cytoplasmic sensors for viral RNAs that activate type I interferon are the RIG-I-like receptors (RLRs). RLRs are a class of pattern recognition receptors (PRRs) that recognize viral RNA molecules and initiate an immune response. These receptors are present in the cytoplasm of cells and include proteins such as RIG-I and MDA5.