Final answer:
Among the list, hypotension is a known adverse reaction to amphotericin B. It can cause disruption of cell membranes leading to side effects, such as nephrotoxicity and hypotension. Serum potassium 5.6 mEq/L suggests hyperkalemia, another possible side effect, but hypotension is the direct answer here.
Step-by-step explanation:
A nurse is evaluating a client who is receiving amphotericin B via intermittent IV bolus and needs to determine which of the following findings indicates an adverse reaction to this medication. Among the options given:
- Serum potassium 5.6 mEq/L
- Hematocrit 55%
- Polyuria
- Hypotension
The correct answer is hypotension. Amphotericin B can cause several adverse reactions, but among the choices provided, hypotension is a known side effect of amphotericin B therapy. This antifungal medication can disrupt cell membranes, impacting not only fungal cells but also potentially the host's cells, leading to various side effects such as nephrotoxicity and hypotension.
Serum potassium of 5.6 mEq/L could indicate hyperkalemia, which is another possible side effect of amphotericin B due to its impact on renal function. However, hypotension is the more direct indication of an adverse reaction among the listed options.