Final answer:
An adverse effect of too much TNF-alpha is the excessive activation of immune system cells and release of cytokines, leading to life-threatening fever, inflammation, and shock.
Step-by-step explanation:
An adverse effect of too much TNF-alpha (tumor necrosis factor-alpha) is the stimulation of excessive activation of immune system cells and release of cytokines (chemical mediators) from immune system cells. This can lead to life-threatening fever, inflammation, and shock. In severe cases, it can result in tissue and organ damage, multiple organ failure, and even death.