Final answer:
The Pribnow box is a consensus sequence found in the promoter region of DNA, indicating the binding site for RNA polymerase, located ten nucleotides upstream from the transcription initiation site (+1 position).
Step-by-step explanation:
When we say the Pribnow box is -10 from the initiation site, we are referring to its position relative to the place where transcription starts, denoted as +1. The Pribnow box is a consensus sequence present in the promoter region of DNA that indicates where RNA polymerase binds to initiate transcription. Therefore, the correct answer to the question is B) It indicates the binding site for RNA polymerase.
The Pribnow box, or TATAAT sequence, is a specific DNA sequence that is crucial for the transcription initiation process in prokaryotic organisms. This box is typically located ten nucleotides upstream from the point where transcription actually starts, which is the +1 position on the DNA sequence. The correct orientation during this process is essential for the proper expression of genes.