Final answer:
The medication class that is not used to treat premenstrual syndrome (PMS) is beta-blockers.
Step-by-step explanation:
The medication class that is NOT used to treat premenstrual syndrome (PMS) is beta-blockers.
Selective serotonin reuptake inhibitors (SSRIs), nonsteroidal anti-inflammatory drugs (NSAIDs), and gonadotropin-releasing hormone (GnRH) agonists are all used to treat PMS.
Beta-blockers, on the other hand, are primarily used to treat high blood pressure and certain heart conditions, and are not commonly prescribed for PMS.