Final answer:
The clinical consequences of congenital heart disease include cyanosis and clubbing.
Step-by-step explanation:
Two clinical consequences of congenital heart disease are cyanosis and clubbing. In the case of severe septal defects, such as tetralogy of Fallot and patent foramen ovale, the failure of the heart to develop properly can result in a condition commonly known as a 'blue baby.' This condition causes insufficient supply of oxygenated blood, leading to a blue or purple coloration of the skin (cyanosis), especially during physical activity. Clubbing is a condition where the fingernails and toenails become rounded and the tips become enlarged, typically associated with chronic lack of oxygen in the blood, such as in congenital heart diseases.