Final answer:
Acanthosis nigricans is a skin condition that indicates insulin resistance, which can be a precursor to developing type 2 diabetes. It can also be a sign of obesity, PCOS, and certain cancers.
Step-by-step explanation:
Acanthosis nigricans is a skin condition characterized by dark, thickened patches of skin. It is most commonly associated with insulin resistance, which is a condition where the body's cells become less responsive to the hormone insulin. Insulin resistance is often a precursor to developing type 2 diabetes. Acanthosis nigricans can also be a sign of other underlying medical conditions such as obesity, polycystic ovary syndrome (PCOS), and certain cancers.