Final answer:
A herniated disc most commonly occurs in the lumbar region of the vertebral column, causing pain and other symptoms in the lower back and legs.
Step-by-step explanation:
A herniated disc most commonly occurs in the lumbar region of the vertebral column. The lumbar region is the lower part of the spine, located in the lower back. It is susceptible to herniation due to the significant range of motion and weight-bearing that this region experiences. Herniated discs can cause pain, numbness, and weakness in the lower back and legs.