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Which drugs are used to treat overflow incontinence (select all that apply)?

a. Baclofen (Lioresal)
b. Anticholinergic drugs
c. α-Adrenergic blockers
d. 5α-reductase inhibitors
e. Bethanechol (Urecholine)

1 Answer

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Final answer:

Bethanechol (Urecholine), a muscarinic agonist, is used to treat overflow incontinence by inducing bladder contractions. Anticholinergic drugs and α-Adrenergic blockers are not typically used for overflow incontinence as they can exacerbate the condition. 5α-reductase inhibitors might be used when overflow incontinence is related to BPH by reducing prostate size.

Step-by-step explanation:

The drugs used to treat overflow incontinence may include Bethanechol (Urecholine), which is a muscarinic agonist that can help to contract the bladder and facilitate urination. However, drugs like anticholinergic drugs and α-Adrenergic blockers are generally not used for overflow incontinence as they can actually worsen the condition by inhibiting bladder contractions and relaxing the bladder neck, respectively. Drugs like 5α-reductase inhibitors may be used in certain types of overflow incontinence related to benign prostatic hyperplasia (BPH) as they can reduce the size of the prostate and potentially relieve the urinary retention causing overflow incontinence.

Discussing the medications used in various conditions, for example, Bethanechol (Urecholine) is a muscarinic agonist and could be considered an antidote to atropine poisoning, which is treated with a muscarinic agonist to counteract the muscarinic receptor blockade caused by anticholinergic drugs like atropine.

Loop diuretics, which are commonly used to treat hypertension, increase urination because they inhibit the reabsorption of Na+ and Cl− in the loop of Henle, which in turn increases urine output.

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