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Solutes that require transport for movement might be too large to pass or might be

A) Small and hydrophobic
B) Large and hydrophobic
C) Small and hydrophilic
D) Large and hydrophilic

1 Answer

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Final answer:

Large and hydrophilic solutes require transport for movement across the cell membrane as they cannot easily cross the phospholipid bilayer.

Step-by-step explanation:

Large polar or ionic molecules which are hydrophilic, cannot easily cross the phospholipid bilayer. Solutes dissolved in water on either side of the cell membrane will tend to diffuse down their concentration gradients but because most substances cannot pass freely through the lipid bilayer of the cell membrane their movement is restricted to protein channels and specialized transport mechanisms in the membrane.

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