Question

Addition of TRK ligand and a drug that inhibits the activity of the phosphatase that acts on SZE

A) Protein synthesis inhibition
B) Increased gene transcription
C) Activation of MAP kinase pathway
D) Inhibition of cell cycle progression

Answer 1

Adding a TRK ligand with a phosphatase inhibitor likely leads to activation of the MAP kinase pathway, which can increase gene transcription and other cellular responses.

Step-by-step explanation:

The question involves identifying the outcome of adding a TRK ligand and a drug that inhibits the activity of a phosphatase that acts on an unspecified substrate 'SZE'. Considering the context provided, the phosphatase inhibitor would likely prevent the dephosphorylation of downstream signaling molecules. Inhibition of phosphatases leads to increased phosphorylation, which in turn can activate various signaling pathways, like the MAP kinase pathway. Since MAP kinase activation is often associated with gene transcription and cellular responses such as proliferation, survival, and differentiation, the most likely outcome here would be the activation of the MAP kinase pathway (C).