Final answer:
Neurofibromatosis type 1 (NF1) can lead to complications such as hypopigmented skin, neuromuscular disorders, and potentially loss of extremities. Patients may also experience neurological symptoms due to tumors affecting the central nervous system.
Step-by-step explanation:
Common complications of neurofibromatosis type 1 (NF1) include a range of clinical manifestations. Patients with NF1 may experience hypopigmented skin, skin lesions, and nodules, often referred to as cafe-au-lait spots or neurofibromas. Due to the nature of the disease affecting nerve tissue, there may be a loss of peripheral nerve function which can lead to a decrease in sensation or movement of affected areas. In extreme cases, NF1 can cause more severe complications such as loss of fingers, toes, and other extremities, as well as neuromuscular disorders that present as symptoms of numbness and tingling. Additionally, NF1 patients may suffer from neurological complications such as nausea, vomiting, photophobia, and a stiff neck, often associated with tumors of the central nervous system. It's important to note that these symptoms and complications can vary significantly from person to person.